5-Hydroxytryptophan (5-HTP) As An Antidepressant

5-HTP is made from a natural substance that is found in the seeds of the Griffonia Simplicifolia plant. This particular plant is a climbing plant that comes from both Central as well as Western Africa. Hydroxytryptophan; which is actually extracted from the seeds of the plant plays an important and natural role in the synthesis of Serotonin. If you’ve been following this blog then you will learn that Serotonin can be very powerful in regulating both sleep and your mood.

Why Take 5-HTP

Some people may consider taking this as a natural supplement as a supplement to an actual, commercially viable anti-depressant. It is actually popular in some parts of Europe as a method to address depression. The reasons can be many, but some people may desire to support a more natural approach to health or have experienced side effects from their current SSRI medication. It’s also important to note that where you may have no or poor success with an anti-depressant med that trying another with the guidance of your health care professional may yield the results that you need.

5-HTP is one natural supplement to consider so long as you consult with your doctor first to make sure that it’s right for you. It can be found in most health food stores, but one thing to remember is that if you find a brand that works for you – stick with it. The truth is that natural supplements are not regulated by the FDA; which means that different natural supplement companies are free to maintain their own dosages of the supplement. Changing from one brand to another may not be a good idea. Always try to stick with one brand consistently.


5-HTP is taken to help with sleep disorders, eating disorders, depression, anxiety and migraines to name a few. Several trials have been conducted that revealed that taking 50 – 3000 MG consistently for 2 or more weeks can ease the symptoms of depression. Other studies have shown that 5-HTP may be just as effective as most, standard anti-depressant medications.

One thing that you don’t want to attempt is to take both an anti-depressant and Hydroxytryptophan alongside each other, because they can interfere with each other. 5-HTP helps to increase Serotonin production to the brain

5-HTP decarboxylates with Serotonin with an L-amino acid and with the help of vitamin B6 through both the liver (where the majority of Serotonin is produced) and nervous tissue.